With the increasing shortage of fossil energy and serious environmental pollution, it is urgent to seek efficient, clean and renewable energy. Hydrogen energy, as a new password of modern energy industry system, has attracted extensive attention in recent years dueto its advantages of cleanliness, renewability, storage and wide range of application. At present, there are many ways to produce hydrogen, but the large-scale, efficient, low-cost and green ways are the basis of the future hydrogen energy economy. Among them, thermochemical sulfur-iodine cycle (iodine-sulfur cycle) is recognized as one of the most promising hydrogen production methods due to itsabove advantages in water splitting hydrogen production. The basic research on the thermochemical sulfur-iodine cycle water splitting hydrogen production was reviewed from three aspects: Bunsen reaction, H2SO4 decomposition and HI decomposition. Secondly, the sulfuriodine cycle systems that had been established in various countries were summarized, and the latest progress in the nuclear energy-coupled sulfur-iodine cycle hydrogen production process was introduced. Finally, the current nuclear energy coupling sulfur-iodine hydrogenproduction was discussed and analyzed from the aspects of economy, environmental protection and safety, in order to provide new ideas forfuture research and development. It is very important to find a new method for efficient separation of reactants in the Bunsen reaction part.The main research for the decomposition of H2SO4 and HI at this stage is still focused on the development of stable, efficient and low-costcatalysts. Thermochemical sulfur-iodine cycle water splitting hydrogen production technology has made great progress after decades of research. The harsh high temperature and high corrosion environment and complex coupling process are the main reasons that limit its scaleand industrialization in actual hydrogen production. Developing corrosion-resistant and heat-resistant systems made of industrial structuralmaterials, and continuing to optimize and simulate coupled processes are the future development directions of thermochemical sulfuriodide cycle water splitting hydrogen production technology.