In order to explore the impact of co-disposal of municipal sludge in coal-fired power stations on the existing equipment systemand operation status of the unit, laboratory co-combustion test and on-site co-combustion test was carried out. The test results show thatwhen dry sludge with 13% water content is mixed with 20% sludge in the laboratory, the ignition temperature of the mixed fuel is increased by 36 ℃ and the burnout rate is decreased by 1.5%. With the increase of sludge proportion, the grindability of fuel decreases andthe tendency for slagging increases. In the field test, the sludge with 40% water content is mixed with 10% or less, the coal handling andpulverizing system operates normally, the boiler coking condition, steam and water parameters, air and smoke parameters are within thenormal range; The maximum toxic equivalent value of dioxin in flue gas is 0.038 ng/ m3(11% O2), the maximum values of HCL and HFare 2.50 and 0.23 mg/ m3.The mass concentration of smoke and dust is≤ 10 mg/ m3, the mass concentration of SO2 is≤ 35 mg/ m3,the mass concentration of NOx is≤ 50 mg/ m3, all of which can meet the national emission standards. The emission of cyanide ion, alkyl mercury, heavy metal and fluorine ion in fly ash, large slag and gypsum meet the requirements of national standards. The results showsthat when the sludge blending ratio is 10% or less, the auxiliary equipment of the unit such as the coal handling system, the pulverizingsystem, the combustion system, the forced draft fan and the induced draft fan can adapt, and will not affect the quality and utilization offly ash, large slag and gypsum, in addition the NOx, SO2, soot, dioxin, HCl and HF in the flue gas can be discharged up to standard.When further increasing the sludge blending ratio, it is still necessary to pay attention to the calculation of drying output and grinding output of the pulverizing system, and monitor the change of furnace flue gas temperature, slagging on the pipe wall and pollutant discharge,so as to reasonably and safely solve the sludge disposal problem.