Abstract: Coal mine ventilation air methane is the associated gas of coal mine, and the main component is methane. A large amount of coal mine ventilation air methane released into the atmosphere has caused ecological problems such as global warming. Therefore, the emission reduction of the ventilation air methane is crucial to achieving the “Double Carbon” target. Catalytic combustion is a promising method for emission reduction of methane, the key lies in the development of low cost and high catalytic activity catalysts. In recent years, perovskite oxides have attracted great attention in the field of methane catalytic combustion due to the advantages of flexible composition, special structure, low cost and regulation of catalytic performance. In the industrial application of perovskite catalyst for low concentration methane, there are problems such as low catalytic performance and sulfur poisoning, which hinder the further development of perovskite oxide catalytic methane combustion system. The regulative structure and synthesis method of perovskite catalyst were introduced, the mechanism of methane catalytic combustion on perovskite catalyst was summarized, the reason of perovskite inactivation caused by the presence of sulfur was analyzed, and the design method of perovskite catalyst to improve catalytic activity and sulfur resistance was emphasized. It was found that by optimizing preparation conditions, element doping, acid solution treatment, and constructing porous new perovskite, the number of surface active sites and oxygen vacancies of perovskite can be increased, meanwhile, the dispersion degree of active components on the catalyst surface can be increased, thus improving the catalytic activity. Finally, the future design direction of methane combustion catalyzed by perovskite catalyst is prospected.