Abstract: In order to fully utilize the biomass resources, a concept of biomass gasification system with coal-fired power plant and supercritical CO2 cycle was presented. The biomass gasification utilization process of this system is highly coupled with coal-fired power plantand supercritical CO2 cycle. After being cooled by carbon dioxide, the syngas is purified and fed to the gas turbine for combustion. Theheat in the flue gas is gradually recovered through the gas turbine, supercritical CO2 cycle and coal-fired power plant feedwater, enhancing the utilization and thus improving the efficiency. Taking a 660 MW coal-fired unit and a 16 t/ h biomass gasification furnace as examples, thermodynamic and economic analysis was conducted through system simulation. The results show that the proposed coupled systemintroduces 46.66 MW of biomass energy and generates an additional 21.09 MW of power, and the efficiency of biomass-to-electric energy can reach up to 45.20% and the exergy efficiency can reach 41.67%, which fully utilizes the energy in the biomass. The net presentvalue of the system is about 404.68 million yuan, and it only takes about 2.94 years to recover the investment, which shows the good economic performance of the system.