Abstract: CO,as one of the main atmospheric pollutants,comes from industrial furnaces,metallurgical industry and exhaust emission of motor vehicle,causing huge emissions of CO and serious environmental pollution. Currently,the catalytic combustion technology is an effective the mainstream technology to effectively limit and eliminate CO,which can realize low-temperature and high-efficiency conversion of CO by introducing catalyst. It has formed industrial application in low-temperature catalytic oxidation fields such as automobile exhaust emission and preferential oxidation of CO,and the effect is remarkable. The Cu-Ce complex oxide catalysts have attracted many researchers attentions due to its advantages of high efficiency at low temperature,long life and low cost,and widely used in the CO catalytic combustion. The research progress of CO catalytic combustion over Cu-Ce catalyst in recent years was reviewed,and the preparation methods,structure-activity relationship and carrier-active component interaction of Cu-Ce catalyst were summed up here. Based on the characterization techniques,in situ experiments and reaction kinetics models,the difference between various reaction pathways were discussed and the micro reaction mechanism of CO catalytic combustion was summarized. At the same time,according to the variation characteristics of CO concentration in different industrial waste gases,the relevant work progress in recent years carried out by high efficiency and clean combustion team from Institute of Mechanics,Chinese Academy of Science was introduced. Finally,the future development direction of CO catalytic combustion reaction is prospected. Taking the converter off gas( CO≤35%) produced during converter steelmaking process,the CO self-sustained catalytic combustion technology was proposed based on the CuCe_(0.75)Zr_(0.25)O_y and industrial honeycomb ceramic catalyst catalyst,and the rule of CO self-sustained combustion under a wide range of CO concentration( induction,flying hot temperature and self-sustaining stages),reaction paths( M-K and L-H mechanisms) and stable-combustion region( lean burn limit,steady temperature field and heat transfer characteristics) were established,which provided a feasible technical solution to realize two-way energysaving between the loss of converter gas from the gas ignition and its own energy recycling. The future research direction is also discussed:the research on CO catalytic combustion reaction mechanism can be further studied by the new efficient nano Cu-Ce catalyst,including a high utilization of active atom,lasting and efficient catalyst via a fine morphology of catalyst preparation method and large-scale production technology. It's good for investigating evolution rule of the support-active component interaction via advanced in situ characterization technology,simulating calculation method,and the quantitative study of CO adsorption-reaction-desorption reaction process is carried out.The catalyst is also encouraged to extend from laboratory to practical industrial application,in order to investigate various properties of catalyst for complex flue gas environment for a long time using. This analysis can be expected to enrich safety control theory of CO catalytic combustion and promote the development of energy saving and emission reduction.