Abstract: The carbonation conversion of the calcium-based sorbent decreases significantly after multiple CO_2 capture cycles,whether the sorbent can be further used efficiently in desulfurization reaction is important issue which deserves concerns. In order to delve into this issue,the high performance calcium-based sorbent and natural limestone sorbent were selected,the carbonation and sulfation reaction performance after multiple CO_2 capture cycles were analyzed and compared by thermal gravimetric analyzer,and the sulfation kinetics characteristics were studied by particle model. The results showed that the rate of carbonation reaction and CO_2 adsorption capacity of the high performance calcium-based sorbents are much higher than those of limestone adsorbent. After multiple cycles of CO_2 capture test,the CO_2 adsorption capacity of high performance calcium-based sorbents is over 10 times higher than that of limestone,and its SO_2 adsorption capacities was improved by 40% than that of limestone. After multiple CO_2 capture reactions,their sulfation abilities are both improved. The improvement of limestone is greater,the sulfation conversion is increased from 26% to 35%,while the sulfation conversion of high performance calcium-based sorbent is increased from 38% to 43%. It is found through particle model calculation that the sulfation process of both sorbents is a first-order reaction related to the concentration of SO_2. After the multiple CO_2 capture cycles,the activation energy of sulfation reaction of limestone decreases by nearly 30%,while that of high performance calcium-based sorbent only decreases by 5%. The results indicate that the desulphurization capacity of two different calcium-based sorbents can be improved to different degrees after multiple CO_2 capture cycles,and both of them can be better used for SO_2 removal.