Abstract: The low-temperature oxidation of coal during storage not only causes heat loss, but also serious environmental pollution. Existing treatment technologies include physical methods such as layered compaction and chemical methods such as spraying flame retardants. Layered compaction requires a lot of manpower and material resources, and spraying flame retardants can cause secondary environmental pollution. Thermodynamic changes of mixed coal during the low-temperature oxidation process were analyzed using thermogravimetric analysis technology. It is found that there is an interactive relationship between coal mixtures of different coal qualities, especially when easy to oxidize coal and non easy to oxidize coal are mixed in a certain proportion, which has an inhibitory effect on the low-temperature oxidation of easy to oxidize coal and reduces heat loss. At the same time, the interactive effect of different mixing ratios is also studied. It is found that when the two types of coal are mixed in a proportion of 50% each, the inhibitory effect is the strongest. In addition, the thermodynamic research results are verified through on-site experiments. The use of mixed coal method to suppress low-temperature oxidation does not require a lot of manpower and material resources compared to layered compaction, and does not cause secondary environmental pollution compared to chemical methods such as spraying flame retardants. It is a green and environmentally friendly low-temperature oxidation treatment method that can be implemented during coal unloading and stacking, which is simple and easy to implement.