Abstract: The concentrated brine from coal chemical reverse osmosis is a typical high-salt and high-organic matter reverse osmosis concentrated water. Currently, high-pressure reverse osmosis concentration and evaporation crystallization are the mainstream technologies for achieving "zero discharge". However, the presence of a high concentration of organic contaminations can lead to membrane pollution, evaporator corrosion, high saline rate, and low whiteness of crystallized salt. These challenges result in the "zero discharge" technology facing issues such as high cost and poor stability. The sources and composition of the concentrated brine from coal chemical reverse osmosis were introduced, the advantages and technical challenges of centralized treatment were analyzed, and the key to achieving "zero discharge" technology by efficient removal of or-ganic contaminations in high-salt environments was proposed. In terms of removing organic contaminations, the research progress on membrane separation, adsorption, and advanced oxidation methods used for sepa-rating or degrading organic matter in coal chemical reverse osmosis.