Abstract: Carbon Capture, Utilization, and Storage （CCUS） is an indispensable technological choice for China to safeguard its energy security and actively and prudently promote carbon neutrality. However, the current scale application and integration level of the full CCUS process technology in China are still lagging and in a state of disorderly planning, and its emission reduction contribution is insufficient to support the CCUS emission reduction demand under the carbon neutrality target. To effectively address this issue, it is necessary to conduct a comprehensive and in-depth study of the key issues in the layout of CCUS clusters and the development strategies for industrialization. Based on this, the domestic and international literatures are organized and summarized from the perspectives of "understanding the problem - analyzing the problem - responding to the problem" on the current state of CCUS technology development, cluster layout optimization, and the design of industrial development strategies. The results show that there is significant heterogeneity in the development level, application mode, and technical costs of CCUS, with economic costs being the primary constraint on their advancement. Current source-sink matching models lack high-precision data support and more comprehensive realistic constraints, and they do not adequately account for carbon utilization pathways beyond CO₂-EOR. Consequently, existing deployment plans are difficult to support the future development needs of CCUS cluster layouts. Additionally, the absence of effective and sustainable incentive policies and commercial models further undermines the economic feasibility of CCUS technologies. Future research should focus on conducting multidimensional assessments of carbon storage and utilization capacities to provide more robust and comprehensive data support for CCUS cluster layouts. It is essential to optimize source-sink matching models and establish integrated CCUS layout plans and phased development tasks aligned with carbon neutrality goals. Moreover, studies should consider the economic characteristics of CCUS, the societal costs of policies, and their systemic impacts on the environment, energy, and economy, to enhance the design and evaluation of industrial and commercial models for CCUS development.