Abstract: In order to determine the best extraction agent of Fischer Tropsch synthesis water complexing and the process conditions of high efficient removal of acidic organic compounds. Trioctylamine (TOA) and tributyl phosphate (TBP) was elected complexing agents and Noctanol was elected diluent and sulfonated kerosene was elected cosolvent to investigate the extraction effect,stratification time,emulsification of different extractants. The impact of extraction stages,agent-water ratio,extraction time and temperature on the extraction rate of acidic organic compounds were studied and the optimum extraction conditions were determined. The stability of the continuous deacidification effect of extractant was studied under the optimum conditions; Finally,the association mechanism of the extraction of acidic organic compounds by complexation extractant was studied. It is concluded that the organic matter in the wastewater is mainly acidic organic matter,and mainly consisted of formic acid,acetic acid,propionic acid and butyric acid; The experimental study on complex extractant show that the extraction effect of TOA is better than TBP,considering the good extraction effect,low economic cost,fast stratification effect and no emulsification,and the best complexing extractant is 20% TOA-30% N-octanol-50% sulfonated kerosene; Through the experimental study,the best extraction deacidification process conditions is that the ratio is 1 ∶ 4,the temperature is 25 ℃,the extraction time is 10 minutes,and the acid organic matter removal rate is stable at 92% after three-stage extraction; Under the optimum extraction conditions,the deacidification rate is about 93% after continuous extraction for 45 h; It is found that the association mechanism of TOA extraction of acidic organic compounds is ion association and hydrogen bond association,and that of TBP extraction of acidic organic compounds is hydrogen bond association.