Abstract: In the SCR system,the denitration efficiency is greatly affected by the performance of the catalyst. The V_2O_5-WO_3/TiO_3 cata-lyst which is widely used is not only expensive,but also the vanadium oxide in the catalyst after deactivation will cause serious pollution tothe environment. Therefore,traditional catalysts need to be improved. The new non-toxic catalyst uses rare earth metal oxide as the ac-tive component,which can greatly reduce the degree of environmental pollution. In order to study the application effect of the new non-tox-ic catalyst in practical engineering,and taking unit 8 of the power plant as an example,the denitration efficiency,ammonia escape rate,and SO_2/SO_3 conversion rate of the SCR denitration system of the unit were tested. Three operating loads of 360,500,and 600 MW weretested,and sampling inspection was carried out on both sides of A and B under each operating condition. The test results show that the av-erage denitration efficiency of the SCR denitration system under 3 operating loads is 82.31%,76.81%,and 81.58% respectively,and thedenitration efficiency of the single-layernon-toxic denitration catalyst is 52.34%,55.34%,and 57.14% respectively,which are all greaterthan guaranteed value of 45%.Under the test load of 600 MW,the average SO_2/SO_3 conversion rate of the newnon-toxic catalyst is 0.38%,which is less than the guaranteed value of 1%,and the resistance of the first-layer catalyst under the three loads is 96,117.5 and 153 Parespectively,which are both less than the guaranteed value of 200 Pa.The average ammonia escape concentrations are 1.26×10~(-6),1.46×10~(-6),and 0.52×10~(-6) respectively,which are less than the guaranteed value of 2.5×10~(-6). The NOxconcentrations at the sides of the denitration system A and B at 360 MW are 38 and 46 mg/m~3.The NOx concentrations at the sides of the denitration system A and B at 500 MW are 21 and 28 mg/m~3. At 600 MW,the denitration system A,B The NOx concentrations at the outlets on both sides of B were 27 and31 mg/m~3,respectively. Under all operating conditions,the NOx concentration in the flue gas on both sides of outlet A and B of the denitra-tion system is lower than the requirements of ultra-low emission standards,and the new non-toxic denitration catalyst can meet the re-quirements of industrial applications.